Authors: Spetale Flavio Ezequiel; Murillo Javier; Tapia Elizabeth; Arce Debora; Ponce Sergio; Bulacio Pilar.
Title: Formal modeling of Gene Ontology annotation predictions based on factor graphs.
Resumen: Gene Ontology (GO) is a hierarchical vocabulary for gene product annotation. Its synergy with machine learning classification methods has been widely used for the prediction of protein functions. Current classification methods rely on heuristics solutions to check the consistency with some aspects of the underlying GO structure. In this work we formalize the GO is-a relationship through predicate logic. Moreover, an ontology model based on Forney Factor Graph (FFG) is shown on a bounded but general enough fragment of Cellular Component GO.
Meeting type: Congreso.
Production: Formal modeling of Gene Ontology annotation predictions based on factor graphs.
Scientific meeting: XX Congreso de Bioingeniería. IX Jornada de Ingeniería Clínica.
Meeting place: San Nicolas.
It's published?: No
Meeting month: 10